Colonoscopy Guide
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Which test?

Choosing a screening test

There is more than one way to screen. The best test is the one you will actually do. Talk with your doctor about your risk and which test suits you.

The main tests

TestWhat it isHow often, if normal
ColonoscopyLooks at the whole colon. Polyps are removed during the same exam.Every 10 years
FIT stool testA stool sample at home, checked for hidden blood.Every year
High-sensitivity guaiac stool testA stool sample at home, checked for hidden blood.Every year
Stool DNA or RNA testA stool sample at home, checked for blood and genetic changes.Every 3 years
CT colonographyA CT scan of the colon. Needs a prep.Every 5 years
Flexible sigmoidoscopyLooks at the lower part of the colon only.Every 5 years
Blood testNot a preferred test. Misses most precancerous polyps. For people who won't do any of the tests above.Ask your doctor

Good to know

  • Any abnormal result needs a colonoscopy. If a stool test, scan or blood test finds something, a colonoscopy is the next step. Screening isn't complete until it is done.
  • Only a colonoscopy can remove polyps during the test itself.
  • Higher risk? If cancer or advanced polyps run in your family, or you have had polyps before, your doctor will usually recommend a colonoscopy.
  • Cost: most health plans cover screening with no copay. Ask your plan what it covers, including a follow-up colonoscopy after an abnormal stool test.
Sources: American Cancer Society screening guideline (revised May 2026); US Preventive Services Task Force (2021); CDC, colorectal cancer screening tests.Clinical review: pending · Review date: pending

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